Scientists relieved as coronavirus vaccine trial restarts — but question lack of transparency

By: David Cyranoski & Smriti Mallapaty - 15 Sept, 2020
Scientists relieved as coronavirus vaccine trial restarts — but question lack of transparency

The UK trial of a leading coronavirus vaccine, which was abruptly halted because of safety concerns, restarted on Saturday after the university conducting the trial said an independent committee found that it was safe to do so.

The University of Oxford and pharmaceutical company AstraZeneca paused enrolment in the global trials of their vaccine candidate on 6 September, after a person participating in the UK trial experienced an adverse reaction.

Scientists say that a pause is not uncommon in large trials, and that a speedy resumption of testing was to be expected. The episode shows that care is being taken with the trial, they say.

“Like anybody else who knows the importance of vaccines, I am very happy that the trial will continue,” says Klaus Stöhr, a retired influenza researcher who headed the World Health Organization’s research and epidemiology division for severe acute respiratory syndrome.

But some scientists have criticized the trial sponsors for not releasing more information about the reason for the pause and their decision-making.

The University of Oxford and AstraZeneca have not yet released details of the adverse reaction that led to the trial’s pause and how the decision to resume the UK study was made. Regulators in Brazil announced that trials of the vaccine restarted on Monday, but it is unclear when similar trials in South Africa and the United States might also resume.

Marie-Paule Kieny, a vaccine researcher at INSERM, the French national health-research institute in Paris, says she hopes that research groups working on this or other coronavirus vaccines will share more information about clinical-trial holds in future. The transparency bar should be set much higher than this latest example, says Kieny. "When ultimately a vaccine will be made available, public trust will be paramount to ensure public-health impact. And trust needs transparency."

(This story has not been edited by VOH and is auto-generated from a syndicated feed.)

suggested Tags

Subscribe Our Newsletter

Four coronavirus vaccines in advanced stages of pre-clinical trial in India
By: Staff Writer - 21 Aug, 2020

News

Four coronavirus vaccines in advanced st

By: Staff Writer-21 Aug, 2020

Coronavirus grows less deadly as doctors

By: Bloomberg-21 Sept, 2020

86,961 new COVID-19 cases in India, tall

By: PTI-21 Sept, 2020

WHO endorses protocol for coronavirus he

By: AFP-21 Sept, 2020

TCS sets up 11 coronavirus isolation cen

By: PTI-21 Sept, 2020

Oxford covid vaccine: AstraZeneca denies

By: Bloomberg-18 Sept, 2020

Government to use immunisation program m

By: Leroy Leo-18 Sept, 2020

Oxford COVID-19 vaccine: Serum Institute

By: Anulekha Ray-19 Sept, 2020

WHO endorses protocol for coronavirus he

By: REUTERS-20 Sept, 2020

When will COVID-19 vaccines be generally

By: Reuters-18 Sept, 2020

COVID Conflicts Are Straining Relationsh

By: Serena Gordon-18 Sept, 2020

COVID Prevention May Mean Record Low Flu

By: Dennis Thompson-18 Sept, 2020

Coffee May Slow Spread of Colon Cancer

By: Alan Mozes-18 Sept, 2020

Rich nations have cornered half of futur

By: AFP-18 Sept, 2020

Oxford covid vaccine: AstraZeneca denies

By: Bloomberg-18 Sept, 2020

Centre approved anti-viral medicines to

By: PTI-17 Sept, 2020

Record 97,894 infections pushes India's

By: PTI-17 Sept, 2020

Can a Parkinson's Drug Treat Macular Deg

By: Serena McNiff-17 Sept, 2020

US emergency approval broadens use of Gi

By: PTI-17 Sept 2020

The poisonous history of chemotherapy

By: Heidi Ledford-16 Sept, 2020

Researchers highlight ‘questionabl

By: Alison Abbott-16 Sept, 2020

The lasting misery of coronavirus long-h

By: Michael Marshall-16 Sept, 2020

Post COVID-19, Lung Function Improves Ov

By: Carolyn Crist-16 Sept, 2020

Stillbirth rate rises dramatically durin

By: Clare Watson-16 Sept, 2020

When will there be a cure for covid? The

By: Michelle Cortez , Bloomberg-15 Sept, 2020

Pfizer’s COVID Vaccine Could Be Gi

By: Anonymous-15 Sept, 2020

Scientists relieved as coronavirus vacci

By: David Cyranoski & Smriti Mallapaty-15 Sept, 2020

China coronavirus vaccine may be ready f

By: Reuters-15 Sept, 2020

Latest on the worldwide spread of corona

By: Reuters-15 Sept, 2020

Bill Gates: ‘The next big question

By: Noah Higgins-Dunn & Christina Farr-15 Sept, 2020

Gilead CEO: We’re studying new way

By: Kevin Stankiewicz-15 Sept, 2020

Business leaders push for inclusivity af

By: Sam Shaed-15 Sept, 2020

Scientists publish images of coronavirus

By: PTI-14 Sept, 2020

How pharma companies can still deliver a

By: Anonymous-13 Sept, 2020

China starts testing world's first nasal

By: Anonymous-13 Sept, 2020

Over 1 lakh health IDs created under Nat

By: Anonymous-13 Sept, 2020

Internet searches for symptoms can revea

By: Anonymous-13 Sept, 2020

Oxford covid-19 vaccine: AstraZeneca mus

By: Anonymous-12 Sept 2020

Oxford-AstraZeneca covid vaccine trials

By: Anonymous-12 Sept 2020

Russia Begins Rollout of COVID-19 Vaccin

By: Ralph Ellis-12 Sept 2020

Coronavirus research updates: Surprise!

By: Anonymous-12 Sept 2020

Scientists Identify New Way to Target So

By: Newsroom-12 Sept 2020

COVID-19 Story Tip: Researchers Expect V

By: Newsroom-12 Sept 2020

Oxford covid-19 vaccine: AstraZeneca m

By: Mint News-10 Sep 2020

Can Plexiglass Stop COVID?

By: Kathleen Doheny-08 Sept 2020

Companies testing vaccines pledge safety

By: Linda A. Johnson-08 Sept 2020

Coronavirus research updates: The immune

By: Nature-09 Sept 2020

AstraZeneca COVID-19 vaccine study pause

By: Lauran Neergaard-09,Sept, 2020

India considering Russia's request for P

By: Surajit Dasgupta-08, Sept, 2020

Trial Tests MMR Vaccine to Help Prevent

By: HealthDay Reporter-04 Sept2 020

India's COVID-19 infection tally crosses

By: PTI-08 Sept, 2020

How to fight the deadly dengue virus? Ma

By: Jon Emont , The Wall Street Journal-08 Sept, 2020

Health-Care Startup Ro Raises $200 Milli

By: John McCormick-08 Sept, 2020

The Latest: Australia OKs funding for tw

By: The Associated Press-08 Sept, 2020

UNICEF to lead global procurement, suppl

By: PTI-08 Sept, 2020

UN: No vaccine to be endorsed before it&

By: AP News-08 Sept, 2020

Transplanted brown-fat-like cells hold p

By: Joslin Diabetes Center-05 Sept, 2020

Russia covid vaccine produces immune res

By: Suzi Ring , Bloomberg-05 Sept, 2020

Covid-19 vaccine developers prepare join

By: Peter Loftus-05 Sept, 2020

COVID-19 Ills No Greater for Those With

By: Robert Preidt-05 Sept, 2020

Asthma May Not Boost Odds of Severe COVI

By: Serena Gordon-05 Sept, 2020

Study Backs Use of Saliva COVID-19 Test

By: Kerry Dooley Young-05 Sept, 2020

Coronavirus research updates: Powerful n

By: Anonymous-05 Sept, 2020

Can COVID-19 Cause Diabetes?

By: Anonymous-04 Sept, 2020

‘CRISPR babies’ are still to

By: Heidi Ledford-04 Sept, 2020

Study: COVID-19 Antibodies May Last 4 Mo

By: WEBMD NEWS BRIEF-04 Sept, 2020

Why A Vaccine Won’t Be a Quick Fix

By: Brenda Goodman, MA-04 Sept, 2020

Tiny Biological Package Gets Drug Right

By: Newsroom-04 Sept, 2020

India's COVID-19 tally crosses 38-lakh m

By: PTI-3 Sept, 2020

Steroids can save lives of critically il

By: Kate Kelland , Reuters-3 Sept, 2020

India will supply coronavirus vaccines t

By: Gayathri Vaidyanathan-03 Sept, 2020

Advisory Group Outlines COVID-19 Vaccine

By: Carolyn Crist-2 Sept, 2020

Covid-19 hit cancer research, funding fo

By: Neetu Chandra Sharma-2 Sept, 2020

Brain Cell Death in ALS, Dementia Tied t

By: Newsroom-2 Sept, 2020

Coronavirus research updates: Even octog

By: Anonymous-2 Sept, 2020

Effective Cancer Immunotherapy Further L

By: Newsroom-2 Sept, 2020

Study reveals immune-system deviations i

By: BRUCE GOLDMAN-2 Sept, 2020

Cancer Cells Take Over Blood Vessels to

By: Newsroom-2 Sept, 2020

Research Story Tip: Motor Learning Proce

By: Newsroom-2 Sept, 2020

GSK, partner Vir join race to find COVID

By: Reuters-1 Sep, 2020

COVID-19 can wipe out health care progre

By: Reuters-1 Sep, 2020

Scientists see downsides to top COVID-19

By: Reuters-1 Sep, 2020

Russia to vaccinate high risk groups aga

By: Reuters-1 Sep, 2020

Explainer: How common cold viruses are b

By: Reuters-1 Sep, 2020

Why deforestation and extinctions make p

By: Jeff Tollefson-1 Sep, 2020

What you need to know about the coronavi

By: Reuters-1 Sep, 2020

Antibody therapies could be a bridge to

By: Heidi Ledford-1 Sep, 2020

FDA commissioner says willing to fast-tr

By: Reuters-30 Aug, 2020

Mutated coronavirus strain found in Indo

By: Reuters-30 Aug, 2020

Research Story Tip: Addition by Division

By: Reuters-18 Aug, 2020

Fad or future? Telehealth expansion eyed

By: Ricardo Alonso-Zaldivar-30 Aug, 2020

India sets global record with single-day

By: Reuters-30 Aug, 2020

Global coronavirus cases surpass 25 mill

By: Reuters-30 Aug, 2020

Exclusive: WHO sweetens terms to join st

By: Reuters-29 Aug, 2020

Moderna in talks with Japan to supply 40

By: Reuters-29 Aug, 2020

The coronavirus is most deadly if you ar

By: Smriti Mallapaty-29 Aug, 2020

Got Fatigue? Study Further Pinpoints Bra

By: Newsroom-29 Aug, 2020

J&J to start mid-stage coronavir

By: Reuters-29 Aug, 2020

Latest on the worldwide spread of corona

By: Reuters-29 Aug, 2020

New reckoning for WHO vaccine plan as go

By: Reuters-29 Aug, 2020

How India's Silicon Valley saw its COVID

By: Sachin Ravikumar, Derek Francis, Nivedita Bhattacharjee-26 Aug, 2020

Coronavirus research updates: Sex differ

By: Reuters-26 Aug, 2020

From ACTH to DNA: the rise of acronyms i

By: Giorgia Guglielmi-21 Aug, 2020

COVID-19 Story Tip: Patient Previously D

By: Reuters-25 Aug, 2020

Why IIT Alumni Council withdraws from de

By: Anulekha Ray-24 Aug, 2020

Russia In Touch With India To Manufactur

By: All India | ANI-26 Aug, 2020

COVID-19 lockdowns blocked flu in some p

By: Andrew Meldrum, Mogomotsi Magome and Lauran Neergaard-26 Aug, 2020

Cambridge university aims for autumn tri

By: LONDON (Reuters)-26 Aug, 2020

Treating Wet Age-Related Macular Degener

By: Dr. Eric Nudleman-25 Aug, 2020

Scientists decode how lungs are damaged

By: PTI-25 Aug, 2020

Serum Institute clarifies on report of c

By: LiveMint-25 Aug, 2020

Takeda to sell Japan consumer health uni

By: Junko Fujita-25 Aug, 2020

Survey finds most Britons reject COVID-1

By: Reuters-25 Aug, 2020

U.S. FDA authorizes use of blood plasma

By: Nandita Bose, Aram Roston-25 Aug, 2020

Coronavirus Updates: Manohar Lal Khattar

By: FP Staff-25 Aug, 2020

Study Adds to Evidence That Odor-Sensing

By: Newsroom-24 Aug, 2020

Covid-19 vaccine update: Pfizer, BioNTec

By: FE Online-24 Aug, 2020

Covid-19 vaccine update: Cuba, N Korea,

By: FE Online-24 Aug, 2020

COVID-19 recovery rate reaches 74.69 per

By: PTI-24 Aug, 2020

COVID-19 caseload in India crosses 30-la

By: PTI-24 Aug, 2020

Factbox: Latest on the worldwide spread

By: Reuters-24 Aug, 2020

India crosses crucial milestone of testi

By: PTI-23 Aug, 2020

COVID-19 diagnostic test: Saliva-based t

By: FE Online-23 Aug, 2020

COVID-19: India adds nearly 70,000 cases

By: FE Online-23 Aug, 2020

Novartis immuno-oncology drug candidate

By: Reuters-23 Aug, 2020

US FDA-approved ointment found to treat,

By: PTI-23 Aug, 2020

Trump says without proof that FDA 'deep

By: Reuters-23 Aug, 2020

Coronavirus Updates: Maharashtra reports

By: FP Staff-21 Aug, 2020

Russia's 'Sputnik V' COVID-19 vaccine to

By: Reuters-21 Aug, 2020

Asia Today: India has record high of 69,

By: AP-21 Aug, 2020

Endless first wave: how Indonesia failed

By: Reuters-21 Aug, 2020

Diagnostics firms eye consolidation

By: livemint-21 Aug, 2020

Accuracy Problems with Widely Used Coron

By: Associated Press-21 Aug, 2020

Coronavirus is Not Ready to Budge, So Wh

By: N C Satpathy-20 Aug, 2020

What Is Digital Health ID? Here’s

By: Jagmeet Singh-20 Aug, 2020

How Much Vitamin C Is Too Much Vitamin C

By: Rupali Dutta-20 Aug, 2020

One in four Indians could have been infe

By: Savio Shetty-20 Aug, 2020

Roche, Regeneron link up on COVID-19 ant

By: Reuters-19 Aug, 2020

Explainer: World Health Organization's s

By: Reuters-19 Aug, 2020

Australia hails vaccine deal as virus su

By: Reuters-19 Aug, 2020

COVID-19: Govt to review guidelines to s

By: FE Online-19 Aug, 2020

Coronavirus vaccine update: India begins

By: FE Online-19 Aug, 2020

Immune response after mild COVID-19 is p

By: Reuters-19 Aug, 2020

Recovered cases 2.93 times the number of

By: livemint-19 Aug, 2020

Study links COVID-19 to rise in childhoo

By: Reuters-19 Aug, 2020

WHO blasts 'vaccine nationalism' in last

By: Reuters-19 Aug, 2020

Novavax begins mid-stage study of COVID-

By: Reuters-18 Aug, 2020

COVID-19 vaccine: Do vaccines need to be

By: FE Online-18 Aug, 2020

Russia to roll out vaccine by end of Aug

By: Financial Express-18 Aug, 2020

Testing of CanSino's COVID-19 candidate

By: Reuters-18 Aug, 2020

COVID-19 warriors will be first to get v

By: PTI-18 Aug, 2020

Covid-19, Cold, Flu or Allergy: Know the

By: HT?Correspondent Hindustan Times-17 Aug, 2020

Eat Right, Smile Bright - Acidic Food an

By: FP Studio-17 Aug, 2020

Coronavirus Updates: Karnataka reports 7

By: FP Staff-17 Aug, 2020

Health ID pilot programme to start with

By: FE Online-17 Aug, 2020

Mexico needs 200 million COVID-19 vaccin

By: Reuters-17 Aug, 2020

Factbox: Latest on worldwide coronavirus

By: Reuters-17 Aug, 2020

The Latest: S. Korea reports largest vir

By: The Associated Press-16 Aug, 2020

PM Modi announces launch of National Dig

By: By EH News Bureau-16 Aug, 2020

Russian doctors wary of rapidly approved

By: Reuters-16 Aug, 2020

Need to wage war against NCDs, not just

By: By EH News Bureau-16 Aug, 2020

COVID-19 during pregnancy shows no affec

By: Dr. Liji Thomas-15 Aug, 2020

Has Delhi flattened COVID-19 curve? Wide

By: CitizeMatters.in-15 Aug, 2020

Acupuncture may help with inflammation a

By: Myupchar-15 Aug, 2020

PM Modi to launch National Digital Healt

By: ET Bureau-15 Aug, 2020

WHO says food safe from coronavirus

By: AFP-15 Aug, 2020

Why flu vaccines do not protect people f

By: ScienceMag.org-15 Aug, 2020

Amid Covid-19 fear, Delhi hospital condu

By: ANI-14 Aug, 2020

A new way to monitor skin cancer: Scient

By: Myupchar-14 Aug, 2020

Covid-19: Human trials of Oxford vaccine

By: FE Online-14 Aug, 2020

Coronavirus India Live: Recovery rate in

By: FE Online-14 Aug, 2020

Zydus Cadila launches Indias cheapest re

By: FE Bureau-14 Aug, 2020

NHA governing board gives nod to the int

By: PTI-14 Aug, 2020

ePharmacies to tap approx 70 million Ind

By: EH News Bureau-14 Aug, 2020

Novavax Reports Encouraging Vaccine Resu

By: Carolyn Crist-05 Aug, 2020

"Patients From Outside": Delhi Health Mi

By: DelhiPress Trust of India-09 Aug, 2020

Billion Covid Vaccine Doses Could Be Ava

By: WorldReuters-06 Aug, 2020

New drug RLF-100 shows dramatic recovery

By: PTI-06 Aug, 2020

Biz of this immunity food not in the bes

By: Mayilvaganan-06 Aug, 2020

Views All

Partners & Associates